American Cranberry (Oxycoccus macrocarpus (Ait.) Pursh) Leaves Extract and Its Amino-Acids Preparation: The Phytochemical and Pharmacological Study

The liver is an organ with several important biofunctions, for which there are very few effective and safe preparations that promote the functioning, protection, regeneration of cells. Sufficiently hepatoprotective activity can be found in plants. aim our study was to investigate chemical composition extract made from American cranberry (Oxycoccus macrocarpus (Ait.) Pursh) leaves its amino-acids as well their possible activity. Using UPLC-MS/MS method, we identified 19 phenolic compounds (8 flavonoids (flavones flavonols), 4 anthocyanins, 3 hydroxycinnamic acids, 2 catechins). prophylactic therapeutic administration cranberry-leaves extracts led a decrease lipid-peroxidation process during tetrachloromethane acute toxic damage rats. As result animal studies, most valine arginine.